When you build from published human clinical studies, the results are already known before the formula is ever made.
Who we are
Core3Vitality is built differently from every other brand in this space. We focus on one top-level mechanism: Nitric Oxide and healthy blood flow. We identified all 4 key pathways that need support, selected the exact ingredients and doses used in published human clinical studies, and built a complete system around them. Product. Program. Support. End to end.
My guarantee to you
Our formula is built from the exact ingredients and doses used in published human clinical studies where those results were already proven.
We are fully transparent in everything we do, which is why we show you the ingredients, the doses, and the clinical studies they were built from.
Do not take my word for it. Scroll down and look for yourself.
— Scott Fleming
Founder, Core3Vitality
Most people think blood pressure problems arrive with warning signs.
They usually don't.
Circulation and nitric oxide production naturally decline as we age.
Stress, poor sleep, modern diets, and everyday inflammation quietly speed up the process.
You can feel completely normal while blood flow struggles beneath the surface.
That's why so many people are surprised by their numbers.
Not because something suddenly went wrong, but because decline happens gradually.
Often long before you "feel" anything.
Helps your body make its own nitric oxide again — the same pathway that drives healthy blood flow and penile vasodilation.
Adds clinically-dosed nitrates proven to maintain healthy flow — directly fuelling the vascular system where it matters most.
Guards nitric oxide from everyday stress and oxidation — keeping the signal strong and the vessels healthy.
Provides the essential minerals your vascular system needs to function — because even the strongest NO signal can't work in a depleted body.
Every dose aligns with the levels shown in research to support healthy circulation, endothelial performance and nitric oxide production.
"Collectively, these studies represent over 500 human subjects and 40+ weeks of observed outcomes."
400 mg nitrates shown to reduce systolic BP by ~7–9 mmHg, with reductions up to 11.2 mmHg observed in adults with elevated blood pressure.
Kapil 2015; Hobbs 2012; Bahadoran 2017
3 g/day L-Citrulline supports circulation and vascular function; human randomized trials show L-Citrulline (3–9 g/day) reduces systolic BP by ~4 mmHg on average.
Barkhidarian 2019; Ochiai 2012; Figueroa 2011
Reduced systolic BP by ~8–11 mmHg and diastolic BP by ~5–7 mmHg within 4–8 weeks in adults with prehypertension or metabolic syndrome.
Sivaprakasapillai 2009; Robinson 2012; Belcaro 2013
Meta-analyses show CoQ10 lowers SBP by ~3–5 mmHg on average; a hypertensive RCT reported ~18 mmHg reduction with 120 mg/day. Endothelial function also improves in meta-analysis.
Burke 2001; Zhao 2022; Gao 2012
Human clinical studies show amla extract supports endothelial function and increases nitric-oxide–related biomarkers, improving vascular health.
Usharani, 2013; Taddei 1998; Juraschek 2012
Enhances nitric-oxide–mediated endothelial function and vascular dilation (FMD).
Mohammadipoor 2022; Wong 2010; Wong 2013
Meta-analyses of randomized trials show magnesium lowers SBP by ~3–4 mmHg and DBP by ~2–3 mmHg while supporting electrolyte balance.
Kass 2012; Zhang 2016; Argeros 2025
Supports healthy electrolyte balance and vascular function; higher potassium intakes have been shown in clinical studies to modestly lower blood pressure.
Whelton 1997; Aburto 2013; He 2005
Supports vascular health by helping reduce inflammatory markers in human studies.
Bao 2010; Hosseini 2021; Foster 2012
*Results shown are based on published studies on individual ingredients, not on PowderMAX as a finished product.
"Promote healthy blood pressure quickly and naturally!"
Dr. Karen Vieira PhD MSM Biomedical Sciences Expert
Natural Blood Pressure Support. Backed By Science.
To my knowledge, no other single-serving cardiovascular wellness product on the market combines this breadth of clinically studied ingredients with this level of formulation quality.
I am Dr. Karen Vieira, a biomedical scientist, experienced in the food industry and as a supplement formulator. With over 26 years of supplement research and formulation experience, I lead a team of other PhDs, plus MDs and PharmDs creating formulations and writing about medical, scientific, and nutritional research.
Did you know that by age 40, your body produces about one-half of the nitric oxide that it produced at age 20? What is nitric oxide and why is it critical to your health?
Nitric oxide is a vasodilator, which means it helps relax and expand your blood vessels, promoting healthy blood pressure and blood flow throughout your body. This helps keep blood circulating smoothly, delivering nutrients and oxygen to the brain, muscles, and organs, including sexual organs and the skin. The drop in nitric oxide production that occurs as we age can lead to several negative consequences, including unhealthy blood pressure levels, an increased risk of heart problems, and poor blood flow to the heart, brain, and sexual organs1. Low nitric oxide levels are also associated with stiffened blood vessels and impaired blood vessel function, both of which are risk factors for heart-related issues2.
Signs of Low Nitric Oxide for Men & Women Include Unhealthy Blood Pressure; Poor Sexual Function (Erections & Libido); Impaired Insulin Responses; Memory Loss; and Loss of Exercise Capacit3!
PowderMAX is a premium complete 3 pathway nitric oxide formula combined with a full cardio-mineral foundation, delivered in an easy-to-take powder form. It is the most comprehensive cardiovascular wellness formulation I have reviewed for this category, with clinically studied ingredients at meaningful servings:
PowderMAX is unmatched in its scope. It covers all three nitric oxide pathways at clinically meaningful servings, layers a complete cardio-mineral foundation, and is delivered in a real-cocoa, MCT-based powder that makes daily compliance easy. To my knowledge, no other single-serving cardiovascular wellness product on the market combines this breadth of clinically studied ingredients with this level of formulation quality.
Dr. Karen Vieira, PhD, MSM Biomedical Sciences Expert
CEO/President,
The Med Writers
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
I started noticing a real difference after about three weeks. More energy, better mornings, and a confidence I hadn't felt in years. I showed my doctor and he just said, "Keep going."
— James T. · Verified Buyer
My circulation felt more stable — but I also started sleeping better and feeling more like myself. That's priceless to me.
— Karen B. · Verified Buyer
I was skeptical. But the science behind this is real. I've cut back on other supplements and feel more in control than I have in years.
— Tom S. · Verified Buyer
I'd tried magnesium, beet capsules, and other powders. With PowderMAX, I felt my energy return within days and finally understood what my body needed.
— Diane G. · Verified Buyer
Every scoop of PowderMAX helps your body restore flow, balance, and energy - the way it was meant to.
Your Daily Essentials
In 2022, I found out my blood pressure was far higher than it should've been. The strange part? I felt completely fine.
That's what shook me.
Because when it comes to your vascular health, you don't usually get a warning shot. Things don't ease you into the problem — they just happen.
My doctor suggested medication. But I wasn't ready to accept a lifelong solution without first understanding what was actually going on inside my body.
I'm an engineer by trade. So I did what I always do when something doesn't quite add up. I went looking for answers.
What kept coming up was nitric oxide. How production drops as we age. How the systems that help blood vessels relax and stay flexible become less efficient over time. And how most supplements only addressed one small part of that process.
That didn't sit right with me.
So I partnered with PhD Bio scientists to stress-test the science properly and look at the full picture — not just what sounded good on a label.
As I started applying what we learned, my own numbers moved steadily in the right direction. In fact I went from 156/95 to 124/66 in just a few weeks.
More importantly, I finally felt like I was working with my body, not guessing. That's when it clicked.
There wasn't a single, well-designed solution that brought everything together in a simple daily routine. So we built one.
PowderMAX exists because when it comes to your vascular health, "close enough" isn't good enough.
"It's the first time a supplement actually made sense. I understand why it works - and I can feel and see the difference."
— Alex, NY · Verified Buyer
We're confident HeartHealth-BP PowderMAX will support your health — because we've seen what it can do for thousands of others. But we also know trust is earned.
That's why we offer a 60-Day Money Back Guarantee — no questions asked.
If you're not seeing a difference… If you don't feel like this is helping… If it's just not for you…
Just send us an email, return any unopened bottles, and we'll issue a full refund.
Zero risk. Just results — or your money back.
HeartHealth-PowderMax is a PhD-formulated supplement designed to naturally support healthy blood pressure by targeting all three nitric oxide pathways, PLUS the 3 critcal minerals needed to balance Blood Pressure.
Many users notice improvements within 2-4 weeks of daily use, though individual results may vary.
It's the only supplement clinically designed to target all three nitric oxide pathways, delivering unmatched results with scientifically validated dosages.
High blood pressure significantly increases the risk of heart disease, strokes, and other serious health issues. Managing it proactively can improve overall well-being and vitality.
PowderMax delivers 530 mg of nitrates per serving, equivalent to 74 capsules of standard beetroot powder. It also targets all pathways and includes antioxidant support, PLUS cardio critical minerals and our Cocoa and MCT Blend making it unmatched in value and efficacy.
